Bicarbonate is an electrolyte used by the body to maintain acid/base balance. (pH). Measures the most prevalent form of total carbon dioxide in the blood which is bicarbonate.

• Elevated levels of CO2 can indicate chronic obstructive pulmonary disease, emphysema, or pneumonia, hypertension, metabolic alkalosis.
• Low levels can indicate cirrhosis or liver failure, diabetic ketoacidosis, metabolic or respiratory acidosis, kidney disease, or aspirin overdose.

Methodology - Enzymatic using phosphoenolpyruvate carboxylase (PEPC)