This profile includes both saliva and dried blood spot tests, and provides a broad assessment of possible hormonal imbalances because they assess sex, adrenal, and thyroid hormone levels. These three hormone systems work in harmony, and an imbalance in one system affects the balance of the others as well. Comprehensive testing allows the health care provider to determine the appropriate treatment to restore balance and achieve overall wellness. The Comprehensive Female Profile II tests only the diurnal cortisol in saliva, while the sex and thyroid hormones are all tested using a dried blood spot specimen. This allows physicians to assess baseline levels before hormone replacement therapy and is ideal for monitoring HRT dosing. A full assessment of thyroid health, including screening for hypo or hyperthyroidism, determining Free T4 levels as well as Free T3 levels, testing for autoimmune thyroid disease, and monitoring thyroid replacement dosage is also included.