PTH is a hormone secreted by the parathyroid glands that is important in bone remodeling. PTH functions as part of a feedback system that involves calcium, phosphorus (as phosphate), and vitamin D.
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
- Used to help diagnose the cause of a low or high calcium level and to help distinguish between parathyroid-related and non-parathyroid-related causes.
- A calcium test is almost always ordered along with PTH to determine the balance between calcium and PTH and the response of the parathyroid glands to changing levels of calcium.
- Most often ordered when calcium regulation is abnormal.
- High doses of biotin (> 5 mg/day) may interfere with assay results. Patient assumed to be refraining from biotin supplementation for at least 3 days prior to blood draw.
