Rheumatoid Factor, IgM by EIA (RDL)

Use: EIA methods have the added advantage of being able to simultaneously detect RF of IgG and IgA subclasses in addition to RF IgM and are not susceptible to prozone. It has become apparent that the specificity and predictive value of the RF test is substantially increased by the detection of all three RF isotypes.

Methodology: Enzyme-linked immunosorbent assay (ELISA)